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Lissa will be introduced to fluorescence in situ hybridization (FISH), which is one of the fundamental techniques used in our lab. She will learn how to screen patient slides for abnormal signal numbers of oncogene and tumor suppressor gene probes, and how to document these results by taking images of these hybridizations, and registering the signal counts in charts. She will also be involved in generating new probes for candidate genes in regions of chromosomal gains or losses. She will be fully responsible for a project working with ductal lavage samples from high risk patients with a heriditary breast cancer background. Lissa will also be introduced to the other main techniques in the lab, like e.g. comparative genomic hybridization (CGH), spectral karyotyping (SKY) and fundamental cytogenetic techniques, like preparing metaphase chromosomes. She will receive a comprehensive training in many aspects of the broad variety of experiments performed in our lab.